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Image Search Results
Journal: Scientific Reports
Article Title: A multifunctional DNA nano-scorpion for highly efficient targeted delivery of mRNA therapeutics
doi: 10.1038/s41598-018-28542-3
Figure Lengend Snippet: Characterization of AptDzy-DNS induced translocation. Confocal microscopy images of SK-BR-3 cells after incubation with 0.5 μM Dzy-DNS without aptamer, HAptDzy-DNS, NAptDzy-DNS, and the mixture of HAptDzy-DNS and NApt-Dzy-DNS for 2 h. Scale bars: 20 μm. (Note: NApt, anti-nucleolin aptamer; HApt, anti-HER2 aptamer; Apt, aptamer).
Article Snippet:
Techniques: Translocation Assay, Confocal Microscopy, Incubation
Journal: Scientific Reports
Article Title: A multifunctional DNA nano-scorpion for highly efficient targeted delivery of mRNA therapeutics
doi: 10.1038/s41598-018-28542-3
Figure Lengend Snippet: Cell cytotoxicity assay and proliferation assay. ( A ) CCK-8 assay of cell viability for SK-BR-3 cells incubated with DNS at various concentration. ( B ) CCK-8 assay of cell viability for SK-BR-3 cells incubated with AptDzy-DNS at different hours. ( C ) RT-PCR characterization of HER2 mRNA expression for SK-BR-3 cells incubated without and with AptDzy-DNS. The data error bars indicate means ± SD (n = 5). * P < 0.05, ** P < 0.01 (two-tailed Student’s t-test), ( D ) Western blot characterization of HER2 expression for SK-BR-3 cells incubated with 0.25 (Lane 1), 0 (Lane 2), 0.5 (Lane 3), 0.25 (Lane 4), and 0.125 (Lane 5) μM AptDzy-DNS.
Article Snippet:
Techniques: Cytotoxicity Assay, Proliferation Assay, CCK-8 Assay, Incubation, Concentration Assay, Reverse Transcription Polymerase Chain Reaction, Expressing, Two Tailed Test, Western Blot